Novel 5-Substituted-1H-tetrazole Derivatives as Potent Glucose and Lipid Lowering Agents.
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چکیده
منابع مشابه
Novel 5-substituted-1H-tetrazole derivatives as potent glucose and lipid lowering agents.
A series of 5-(4-alkoxyphenylalkyl)-1H-tetrazole derivatives, containing an oxazole-based group at the alkoxy moiety, was prepared and their antidiabetic effects were evaluated in two genetically obese and diabetic animal models, KKAy mice and Wistar fatty rats. Syntheses were performed by cyclization of the corresponding nitrites reacting with azide compounds. A large number of the 5-(4-alkoxy...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2002
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.50.100